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Image Search Results
Journal: CPT: Pharmacometrics & Systems Pharmacology
Article Title: Multi‐phase multi‐layer mechanistic dermal absorption (MPML MechDermA) model to predict local and systemic exposure of drug products applied on skin
doi: 10.1002/psp4.12814
Figure Lengend Snippet: Schematic representation of the multiphase, multilayer mechanistic dermal absorption (MPML MechDermA) Model Structure within the Simcyp Simulator. API, active pharmaceutical ingredient.
Article Snippet: The latter is being made possible by the integration of the
Techniques:
Journal: CPT: Pharmacometrics & Systems Pharmacology
Article Title: Multi‐phase multi‐layer mechanistic dermal absorption (MPML MechDermA) model to predict local and systemic exposure of drug products applied on skin
doi: 10.1002/psp4.12814
Figure Lengend Snippet: Available QSAR models for predicting various parameters in the MPML MechDermA (default methods in bold)
Article Snippet: The latter is being made possible by the integration of the
Techniques: Fat, Modification, Clinical Proteomics, Protein Binding, Diffusion-based Assay, Viscosity, Molecular Weight, Derivative Assay, Binding Assay, Permeability, Adsorption, Concentration Assay
Journal: CPT: Pharmacometrics & Systems Pharmacology
Article Title: Multi‐phase multi‐layer mechanistic dermal absorption (MPML MechDermA) model to predict local and systemic exposure of drug products applied on skin
doi: 10.1002/psp4.12814
Figure Lengend Snippet: Simulated and observed (mean + SD) SC thickness for different anatomic skin sites provided by the multiphase, multilayer mechanistic dermal absorption (MPML MechDermA) model. Observed data were extracted from relevant literature sources. SC, stratum corneum.
Article Snippet: The latter is being made possible by the integration of the
Techniques: